Claude 自主设计 17 种可结合蝎毒蛋白的分子
Claude 自己跑完了蛋白质设计全流程，从 31 万个分子里筛出 17 个能抓住蝎毒的，两家实验室都验证了。
Anthropic 让 Claude 以智能体形式运行完整的蛋白质设计流程：从 318,484 个候选分子中自设评分标准，筛出 180 个送交合成。在测试的 211 个设计中，17 个成功结合蝎神经毒素，由 Adaptyv Bio 和 Twist Bioscience 两家实验室确认。这项工作由没有蛋白质专业背景的金融公司 Citrini Research 委托。蝎蜇伤每年导致超过 3,250 人死亡，但 Anthropic 明确表示这不是抗蛇毒血清，因为相关验证试验尚未进行。
Claude did the protein scientist’s job and came back with 17 molecules that grip scorpion neurotoxins.
Claude, running as an agent inside Anthropic’s Claude Science setup, ran the whole protein-design campaign itself:
it picked which patch of each scorpion toxin to attack, drove 12 protein-design programs, set its own scoring cutoffs, and chose 180 molecules out of the 318,484 it generated for physical synthesis, and 17 of the 211 designs tested bound their toxin at Adaptyv Bio and Twist Bioscience.
Citrini Research, a finance firm with no lab and no protein expertise, asked for this work, and Claude designed proteins that two labs confirmed latch onto scorpion venom toxins.
Scorpion stings kill more than 3,250 people a year, so the prize is real, if this method works. However, Anthropic is not calling this an antivenom, because the test that would justify the word has not been run yet.
